Verapamil‐containing silicone gel reduces scar hypertrophy

Scar Reducing Effect of the Silicone Gel Sheet with Verapamil in a Rabbit Model of Hypertrophic Scar.

RESULTS: The mean SEI, fibroblast counts, and capillary counts differed significantly among the five groups (P < 0.05). The median SEI was significantly lower in the SGS+2.5 mg verapamil/g group (Figure 1) than in the SGS group (Figure 2) (1.2 vs. 2.2). The median number of fibroblasts was significantly lower in the SGS+0.25 mg verapamil/g group than in the SGS group (172.5 vs. 243). The median...

Silicone Gel Breast Implants

Successful treatment of thyroidectomy scar with a pneumatic needleless injector and silicone gel.

Dear Editors, Thyroidectomy is the most frequently used method when performing surgery for thyroid cancer. A transverse incision on the neck is typically used to approach the thyroid; scar formation in highly visible areas of the neck is a consequence of using this method. The mean score of the Dermatology Life Quality Index for persons who have a thyroidectomy scar is similar to the mean score...

KELO-COTE Silicone Gel For Scar Treatment: First Experience of Application in Russia

A scar is a mass that changes during the passage of time and whose evolution occurs “on the brink of physiology and pathology” [1]. For decades, scars were a fact of life that everyone accepted and had come to terms with. Patients were advised that little could be done and that they had to become accustomed to their scars over time. However, most patients would prefer even the slightest improve...

Biological effects of silicone gel sheeting.

Since silicone gels were first used in the treatment of hypertrophic scars (HS) and keloids (K) they have proved useful and safe. Depending on the specific investigation, the application of silicone gels showed improvements in redness, itching, texture and thickness of HS and K in 60% to 100% of cases. Generally, texture was the first scar characteristic to change, followed by color and height....